Viral vectors for vaccine applications
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چکیده
منابع مشابه
Viral vectors for vaccine applications
Traditional approach of inactivated or live-attenuated vaccine immunization has resulted in impressive success in the reduction and control of infectious disease outbreaks. However, many pathogens remain less amenable to deal with the traditional vaccine strategies, and more appropriate vaccine strategy is in need. Recent discoveries that led to increased understanding of viral molecular biolog...
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Recombinant vectors can be used to deliver antigens and to stimulate immune responses in humans. Viral vectors possess various intrinsic properties which may lend to advantages and disadvantages for usage for a given therapeutic application [reviewed by Larocca and Schlom] [1]. The safety and flexibility of recombinant viral vectors have lead to their usage in gene therapy, virotherapy, and vac...
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Over the last few years the development of plant viral vectors for protein expression has made rapid and impressive progress. Plant viruses are versatile vectors for production of proteins since they are easy to manipulate, quick to evaluate and offer the possibility of great production yields. They are particularly powerful expression systems for the production of recombinant proteins and pept...
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Recent progress in tumor genetics, tumor biology, and tumor immunology has renewed interest in the development of tumor vaccines. Unlike the previous generation of vaccines that consisted of the patient's own tumor cells in some form, the new vaccines contain defined peptides or genes with a known function. In order to induce a potent and long-lasting cell-mediated antitumor response, viral as ...
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Introduction overview of the gene therapy field The gene therapy field has met with serious problems in the clinic that have overshadowed its tremendous potential. The death of an individual enrolled in a gene therapy trial at the University of Pennsylvania and the occurrence of leukemia in three children enrolled in the X-SCID (X-linked severe combined immunodeficiency disease) gene therapy tr...
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ژورنال
عنوان ژورنال: Clinical and Experimental Vaccine Research
سال: 2013
ISSN: 2287-3651,2287-366X
DOI: 10.7774/cevr.2013.2.2.97